A new study reveals Pycnogenol, pine bark extract from the French maritime pine tree, reduces jet lag in passengers by nearly 50%. The two-part study,consisting of a brain CT scan and a scoring system, showed Pycnogenol lowered symptoms of jet lag such as fatigue, headaches, insomnia and brain edema(swelling) in both healthy individuals and patients with high blood pressure. Passengers also experienced minimal lower leg edema, a common condition associated with long flights.
Source: Medical News Today, Nov 6, 2008